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PRDX2 in Myocyte Hypertrophy and Survival is Mediated by TLR4 in Acute Infarcted Myocardium

Peroxiredoxin 2 (PRDX2) is an antioxidant and molecular chaperone that can be secreted from tumor cells. But the role of PRDX2 in acute myocardial infarction (AMI) is not clear. In the current study, we demonstrate the role of PRDX2 from clinical trials, H9c2 cells and in a mouse model. ELISA analys...

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Detalles Bibliográficos
Autores principales: Jin, Xian, Chen, Chengjun, Li, Dandan, Su, Qian, Hang, Yanwen, Zhang, Peng, Hu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539327/
https://www.ncbi.nlm.nih.gov/pubmed/28765537
http://dx.doi.org/10.1038/s41598-017-06718-7