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Live cell screening platform identifies PPARδ as a regulator of cardiomyocyte proliferation and cardiac repair

Zebrafish can efficiently regenerate their heart through cardiomyocyte proliferation. In contrast, mammalian cardiomyocytes stop proliferating shortly after birth, limiting the regenerative capacity of the postnatal mammalian heart. Therefore, if the endogenous potential of postnatal cardiomyocyte p...

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Detalles Bibliográficos
Autores principales: Magadum, Ajit, Ding, Yishu, He, Lan, Kim, Teayoun, Vasudevarao, Mohankrishna Dalvoy, Long, Qinqiang, Yang, Kevin, Wickramasinghe, Nadeera, Renikunta, Harsha V, Dubois, Nicole, Weidinger, Gilbert, Yang, Qinglin, Engel, Felix B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539351/
https://www.ncbi.nlm.nih.gov/pubmed/28621328
http://dx.doi.org/10.1038/cr.2017.84