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Live cell screening platform identifies PPARδ as a regulator of cardiomyocyte proliferation and cardiac repair
Zebrafish can efficiently regenerate their heart through cardiomyocyte proliferation. In contrast, mammalian cardiomyocytes stop proliferating shortly after birth, limiting the regenerative capacity of the postnatal mammalian heart. Therefore, if the endogenous potential of postnatal cardiomyocyte p...
Autores principales: | Magadum, Ajit, Ding, Yishu, He, Lan, Kim, Teayoun, Vasudevarao, Mohankrishna Dalvoy, Long, Qinqiang, Yang, Kevin, Wickramasinghe, Nadeera, Renikunta, Harsha V, Dubois, Nicole, Weidinger, Gilbert, Yang, Qinglin, Engel, Felix B |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539351/ https://www.ncbi.nlm.nih.gov/pubmed/28621328 http://dx.doi.org/10.1038/cr.2017.84 |
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