Combining dendritic cells and B cells for presentation of oxidised tumour antigens to CD8(+) T cells

The dendritic cell (DC) is the foremost antigen-presenting cell (APC) for ex vivo expansion of tumour-specific patient T cells. Despite marked responses in some patients following reinfusion of DC-activated autologous or HLA-matched donor T cells, overall response rates remain modest in solid tumour...

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Detalles Bibliográficos
Autores principales: Grant, Melanie L, Shields, Nicholas, Neumann, Silke, Kramer, Katrin, Bonato, Andrea, Jackson, Christopher, Baird, Margaret A, Young, Sarah L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539416/
https://www.ncbi.nlm.nih.gov/pubmed/28791124
http://dx.doi.org/10.1038/cti.2017.28

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539416/
https://www.ncbi.nlm.nih.gov/pubmed/28791124
http://dx.doi.org/10.1038/cti.2017.28

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