Altered N-Linked Glycosylation in Follicular Lymphoma and Chronic Lymphocytic Leukemia: Involvement in Pathogenesis and Potential Therapeutic Targeting

B-cell antigen receptor (BCR) expression is indispensable for survival of most B-cell malignancies. In follicular lymphoma (FL), N-linked glycosylation sites are introduced in the immunoglobulin (Ig) variable region genes. Oligosaccharides added to the acquired sites are unusually of the high-mannos...

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Detalles Bibliográficos
Autores principales: Hollander, Nurit, Haimovich, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539419/
https://www.ncbi.nlm.nih.gov/pubmed/28824637
http://dx.doi.org/10.3389/fimmu.2017.00912

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539419/
https://www.ncbi.nlm.nih.gov/pubmed/28824637
http://dx.doi.org/10.3389/fimmu.2017.00912

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