Dengue Virus-Infected Dendritic Cells, but Not Monocytes, Activate Natural Killer Cells through a Contact-Dependent Mechanism Involving Adhesion Molecules

Natural killer (NK) cells play a protective role against dengue virus (DENV) infection, but the cellular and molecular mechanisms are not fully understood. Using an optimized humanized mouse model, we show that human NK cells, through the secretion of gamma interferon (IFN-γ), are critical in the ea...

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Detalles Bibliográficos
Autores principales: Costa, Vivian Vasconcelos, Ye, Weijian, Chen, Qingfeng, Teixeira, Mauro Martins, Preiser, Peter, Ooi, Eng Eong, Chen, Jianzhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539423/
https://www.ncbi.nlm.nih.gov/pubmed/28765218
http://dx.doi.org/10.1128/mBio.00741-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539423/
https://www.ncbi.nlm.nih.gov/pubmed/28765218
http://dx.doi.org/10.1128/mBio.00741-17

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