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The domain architecture of large guanine nucleotide exchange factors for the small GTP-binding protein Arf

BACKGROUND: Small G proteins, which are essential regulators of multiple cellular functions, are activated by guanine nucleotide exchange factors (GEFs) that stimulate the exchange of the tightly bound GDP nucleotide by GTP. The catalytic domain responsible for nucleotide exchange is in general asso...

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Detalles Bibliográficos
Autores principales: Mouratou, Barbara, Biou, Valerie, Joubert, Alexandra, Cohen, Jean, Shields, David J, Geldner, Niko, Jürgens, Gerd, Melançon, Paul, Cherfils, Jacqueline
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC553965/
https://www.ncbi.nlm.nih.gov/pubmed/15717927
http://dx.doi.org/10.1186/1471-2164-6-20