Cargando…
EMQIT: a machine learning approach for energy based PWM matrix quality improvement
BACKGROUND: Transcription factor binding affinities to DNA play a key role for the gene regulation. Learning the specificity of the mechanisms of binding TFs to DNA is important both to experimentalists and theoreticians. With the development of high-throughput methods such as, e.g., ChiP-seq the ne...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539975/ https://www.ncbi.nlm.nih.gov/pubmed/28764727 http://dx.doi.org/10.1186/s13062-017-0189-y |