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Contribution of rare and low-frequency whole-genome sequence variants to complex traits variation in dairy cattle

BACKGROUND: Whole-genome sequencing and imputation methodologies have enabled the study of the effects of genomic variants with low to very low minor allele frequency (MAF) on variation in complex traits. Our objective was to estimate the proportion of variance explained by imputed sequence variants...

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Detalles Bibliográficos
Autores principales: Zhang, Qianqian, Calus, Mario P. L., Guldbrandtsen, Bernt, Lund, Mogens Sandø, Sahana, Goutam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539983/
https://www.ncbi.nlm.nih.gov/pubmed/28764638
http://dx.doi.org/10.1186/s12711-017-0336-z