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Contribution of rare and low-frequency whole-genome sequence variants to complex traits variation in dairy cattle
BACKGROUND: Whole-genome sequencing and imputation methodologies have enabled the study of the effects of genomic variants with low to very low minor allele frequency (MAF) on variation in complex traits. Our objective was to estimate the proportion of variance explained by imputed sequence variants...
Autores principales: | Zhang, Qianqian, Calus, Mario P. L., Guldbrandtsen, Bernt, Lund, Mogens Sandø, Sahana, Goutam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539983/ https://www.ncbi.nlm.nih.gov/pubmed/28764638 http://dx.doi.org/10.1186/s12711-017-0336-z |
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