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Fork Head Box Class O1 (FOXO1) Activates Bim Expression to Mediate Cardiac Apoptosis in Chronic Intermittent Hypoxia-Induced Cardiac Hypertrophy

BACKGROUND: Obstructive sleep apnea syndrome (OSAS) is characterized by chronic intermittent episodes of upper-airway obstruction with hypoxia and is associated with increased risk of cardiovascular diseases, including myocardial hypertrophy. Chronic intermittent hypoxia (CIH) has been shown to indu...

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Detalles Bibliográficos
Autores principales: Li, Guangcai, Jin, Meng, He, Yuan, Ren, Jie, Zhang, Minghua, Chen, Yilin, Lan, Xiong, Zhong, Jianhua, Liu, Huiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540011/
https://www.ncbi.nlm.nih.gov/pubmed/28738025
http://dx.doi.org/10.12659/MSM.905210