Cargando…
Improved sequence variant analysis strategy by automated false positive removal
Sequence variant analysis (SVA) is critical in therapeutic protein development because it ensures the absence of genetic mutations of a production clone or high-level misincorporations during cell culture. While software for searching sequence variants from mass spectrometry data are available, effe...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540081/ https://www.ncbi.nlm.nih.gov/pubmed/28590201 http://dx.doi.org/10.1080/19420862.2017.1336591 |