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Improved sequence variant analysis strategy by automated false positive removal

Sequence variant analysis (SVA) is critical in therapeutic protein development because it ensures the absence of genetic mutations of a production clone or high-level misincorporations during cell culture. While software for searching sequence variants from mass spectrometry data are available, effe...

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Detalles Bibliográficos
Autores principales: Li, Wenzhou, Wypych, Jette, Duff, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540081/
https://www.ncbi.nlm.nih.gov/pubmed/28590201
http://dx.doi.org/10.1080/19420862.2017.1336591

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