T(FH)-derived dopamine accelerates productive synapses in germinal centres

Protective high-affinity antibody responses depend on competitive selection of B cells carrying somatically mutated B-cell receptors by follicular helper T (T(FH)) cells in germinal centres. The rapid T-B-cell interactions that occur during this process are reminiscent of neural synaptic transmissio...

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Detalles Bibliográficos
Autores principales: Papa, Ilenia, Saliba, David, Ponzoni, Maurilio, Bustamante, Sonia, Canete, Pablo F., Gonzalez-Figueroa, Paula, McNamara, Hayley A., Valvo, Salvatore, Grimbaldeston, Michele, Sweet, Rebecca A., Vohra, Harpreet, Cockburn, Ian A., Meyer-Hermann, Michael, Dustin, Michael L., Doglioni, Claudio, Vinuesa, Carola G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540173/
https://www.ncbi.nlm.nih.gov/pubmed/28700579
http://dx.doi.org/10.1038/nature23013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540173/
https://www.ncbi.nlm.nih.gov/pubmed/28700579
http://dx.doi.org/10.1038/nature23013

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