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AKT1(low) quiescent cancer cells persist after neoadjuvant chemotherapy in triple negative breast cancer

BACKGROUND: Absence of pathologic complete response (pCR) to neoadjuvant chemotherapy (NACT) correlates with poor long-term survival in patients with triple negative breast cancer (TNBC). These incomplete treatment responses are likely determined by mechanisms that enable cancer cells to resist bein...

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Detalles Bibliográficos
Autores principales: Kabraji, Sheheryar, Solé, Xavier, Huang, Ying, Bango, Clyde, Bowden, Michaela, Bardia, Aditya, Sgroi, Dennis, Loda, Massimo, Ramaswamy, Sridhar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540189/
https://www.ncbi.nlm.nih.gov/pubmed/28764807
http://dx.doi.org/10.1186/s13058-017-0877-7