A brain proteomic investigation of rapamycin effects in the Tsc1(+/−) mouse model

BACKGROUND: Tuberous sclerosis complex (TSC) is a rare monogenic disorder characterized by benign tumors in multiple organs as well as a high prevalence of epilepsy, intellectual disability and autism. TSC is caused by inactivating mutations in the TSC1 or TSC2 genes. Heterozygocity induces hyperact...

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Detalles Bibliográficos
Autores principales: Wesseling, Hendrik, Elgersma, Ype, Bahn, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540199/
https://www.ncbi.nlm.nih.gov/pubmed/28775826
http://dx.doi.org/10.1186/s13229-017-0151-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540199/
https://www.ncbi.nlm.nih.gov/pubmed/28775826
http://dx.doi.org/10.1186/s13229-017-0151-y

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