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Early detection of the aflatoxin B(1) mutational fingerprint: A diagnostic tool for liver cancer

Using duplex-consensus sequencing technology, we recently identified the characteristic high-resolution mutational spectrum of the liver carcinogen aflatoxin B(1) in a mouse model, many months before aflatoxin-induced tumors are detectable. The diagnostic power of this spectrum is then demonstrated...

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Detalles Bibliográficos
Autores principales: Fedeles, Bogdan I., Chawanthayatham, Supawadee, Croy, Robert G., Wogan, Gerald N., Essigmann, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540215/
https://www.ncbi.nlm.nih.gov/pubmed/28868344
http://dx.doi.org/10.1080/23723556.2017.1329693