Influence of the Number of Axial Bexarotene Ligands on the Cytotoxicity of Pt(IV) Analogs of Oxaliplatin

We present the synthesis and cytotoxic potencies of new Pt(IV) complexes with bexarotene, an anticancer drug that induces cell differentiation and apoptosis via selective activation of retinoid X receptors. In these complexes bexarotene is positioned as an axial ligand. The complex of one bexarotene...

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Detalles Bibliográficos
Autores principales: Nosova, Yulia N., Zenin, Ilia V., Maximova, Varvara P., Zhidkova, Ekaterina M., Kirsanov, Kirill I., Lesovaya, Ekaterina A., Lobas, Anna A., Gorshkov, Mikhail V., Kovaleva, Olga N., Milaeva, Elena R., Galanski, Markus, Keppler, Bernhard K., Nazarov, Alexey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540250/
https://www.ncbi.nlm.nih.gov/pubmed/28804273
http://dx.doi.org/10.1155/2017/4736321

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540250/
https://www.ncbi.nlm.nih.gov/pubmed/28804273
http://dx.doi.org/10.1155/2017/4736321

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