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A bimodal activation mechanism underlies scorpion toxin–induced pain

Venomous animals use peptide toxins for hunting and self-defense. To achieve these goals, toxins need to bind to their targets with high affinity due to the small amount that a single bite or sting can deliver. The scorpion toxin BmP01 is linked to sting-induced excruciating pain; however, the repor...

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Detalles Bibliográficos
Autores principales: Yang, Shilong, Yang, Fan, Zhang, Bei, Lee, Bo Hyun, Li, Bowen, Luo, Lei, Zheng, Jie, Lai, Ren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540258/
https://www.ncbi.nlm.nih.gov/pubmed/28782041
http://dx.doi.org/10.1126/sciadv.1700810