β3 integrin expression is required for invadopodia-mediated ECM degradation in lung carcinoma cells

Cancer related deaths are primarily due to tumor metastasis. To facilitate their dissemination to distant sites, cancer cells develop invadopodia, actin-rich protrusions capable of degrading the surrounding extracellular matrix (ECM). We aimed to determine whether β3 integrin participates in invadop...

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Detalles Bibliográficos
Autores principales: Peláez, Rafael, Morales, Xabier, Salvo, Elizabeth, Garasa, Saray, Ortiz de Solórzano, Carlos, Martínez, Alfredo, Larrayoz, Ignacio M., Rouzaut, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540285/
https://www.ncbi.nlm.nih.gov/pubmed/28767724
http://dx.doi.org/10.1371/journal.pone.0181579

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540285/
https://www.ncbi.nlm.nih.gov/pubmed/28767724
http://dx.doi.org/10.1371/journal.pone.0181579

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