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β3 integrin expression is required for invadopodia-mediated ECM degradation in lung carcinoma cells
Cancer related deaths are primarily due to tumor metastasis. To facilitate their dissemination to distant sites, cancer cells develop invadopodia, actin-rich protrusions capable of degrading the surrounding extracellular matrix (ECM). We aimed to determine whether β3 integrin participates in invadop...
Autores principales: | Peláez, Rafael, Morales, Xabier, Salvo, Elizabeth, Garasa, Saray, Ortiz de Solórzano, Carlos, Martínez, Alfredo, Larrayoz, Ignacio M., Rouzaut, Ana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540285/ https://www.ncbi.nlm.nih.gov/pubmed/28767724 http://dx.doi.org/10.1371/journal.pone.0181579 |
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