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Bi-stability in type 2 diabetes mellitus multi-organ signalling network
Type 2 diabetes mellitus (T2DM) is believed to be irreversible although no component of the pathophysiology is irreversible. We show here with a network model that the apparent irreversibility is contributed by the structure of the network of inter-organ signalling. A network model comprising all kn...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540287/ https://www.ncbi.nlm.nih.gov/pubmed/28767672 http://dx.doi.org/10.1371/journal.pone.0181536 |