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Bi-stability in type 2 diabetes mellitus multi-organ signalling network

Type 2 diabetes mellitus (T2DM) is believed to be irreversible although no component of the pathophysiology is irreversible. We show here with a network model that the apparent irreversibility is contributed by the structure of the network of inter-organ signalling. A network model comprising all kn...

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Detalles Bibliográficos
Autores principales: Kulkarni, Shubhankar, Sharda, Sakshi, Watve, Milind
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540287/
https://www.ncbi.nlm.nih.gov/pubmed/28767672
http://dx.doi.org/10.1371/journal.pone.0181536