CRISPR-Cas systems exploit viral DNA injection to establish and maintain adaptive immunity

CRISPR-Cas systems provide protection against viral(1) and plasmid(2) infection by capturing short DNA sequences from these invaders and integrating them into the CRISPR locus of the prokaryotic host(1). These sequences, known as spacers, are transcribed into short RNA guides(3–5) that specify the c...

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Detalles Bibliográficos
Autores principales: Modell, Joshua W., Jiang, Wenyan, Marraffini, Luciano A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540373/
https://www.ncbi.nlm.nih.gov/pubmed/28355179
http://dx.doi.org/10.1038/nature21719

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540373/
https://www.ncbi.nlm.nih.gov/pubmed/28355179
http://dx.doi.org/10.1038/nature21719

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