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CRISPR-Cas systems exploit viral DNA injection to establish and maintain adaptive immunity
CRISPR-Cas systems provide protection against viral(1) and plasmid(2) infection by capturing short DNA sequences from these invaders and integrating them into the CRISPR locus of the prokaryotic host(1). These sequences, known as spacers, are transcribed into short RNA guides(3–5) that specify the c...
Autores principales: | Modell, Joshua W., Jiang, Wenyan, Marraffini, Luciano A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540373/ https://www.ncbi.nlm.nih.gov/pubmed/28355179 http://dx.doi.org/10.1038/nature21719 |
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