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Anabolic role of lysyl oxidase like-2 in cartilage of knee and temporomandibular joints with osteoarthritis

BACKGROUND: Lysyl oxidase like-2 (LOXL2) is a copper-dependent amine oxidase. Our previous studies showed that LOXL2 is elevated during mouse fracture healing. The goal of this study was to evaluate the potential of LOXL2 to act as an anabolic agent in cartilage affected by osteoarthritis (OA). METH...

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Detalles Bibliográficos
Autores principales: Alshenibr, Weam, Tashkandi, Mustafa M., Alsaqer, Saqer F., Alkheriji, Yazeed, Wise, Amelia, Fulzele, Sadanand, Mehra, Pushkar, Goldring, Mary B., Gerstenfeld, Louis C., Bais, Manish V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540418/
https://www.ncbi.nlm.nih.gov/pubmed/28764769
http://dx.doi.org/10.1186/s13075-017-1388-8