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Distinct effects of EGFR inhibitors on epithelial- and mesenchymal-like esophageal squamous cell carcinoma cells

BACKGROUND: Epidermal growth factor receptor (EGFR) plays a pivotal role in the pathophysiology of esophageal squamous cell carcinoma (ESCC). However, the clinical effects of EGFR inhibitors on ESCC are controversial. This study sought to identify the factors determining the therapeutic efficacy of...

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Detalles Bibliográficos
Autores principales: Yoshioka, Masahiro, Ohashi, Shinya, Ida, Tomomi, Nakai, Yukie, Kikuchi, Osamu, Amanuma, Yusuke, Matsubara, Junichi, Yamada, Atsushi, Miyamoto, Shin’ichi, Natsuizaka, Mitsuteru, Nakagawa, Hiroshi, Chiba, Tsutomu, Seno, Hiroshi, Muto, Manabu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540425/
https://www.ncbi.nlm.nih.gov/pubmed/28764725
http://dx.doi.org/10.1186/s13046-017-0572-7