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Comparison between micro- and nanosized copper oxide and water soluble copper chloride: interrelationship between intracellular copper concentrations, oxidative stress and DNA damage response in human lung cells

BACKGROUND: Nano- and microscale copper oxide particles (CuO NP, CuO MP) are applied for manifold purposes, enhancing exposure and thus the potential risk of adverse health effects. Based on the pronounced in vitro cytotoxicity of CuO NP, systematic investigations on the mode of action are required....

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Detalles Bibliográficos
Autores principales: Strauch, Bettina Maria, Niemand, Rebecca Katharina, Winkelbeiner, Nicola Lisa, Hartwig, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540434/
https://www.ncbi.nlm.nih.gov/pubmed/28764715
http://dx.doi.org/10.1186/s12989-017-0209-1