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Reconstructing human pancreatic differentiation by mapping specific cell populations during development

Information remains scarce on human development compared to animal models. Here, we reconstructed human fetal pancreatic differentiation using cell surface markers. We demonstrate that at 7weeks of development, the glycoprotein 2 (GP2) marks a multipotent cell population that will differentiate into...

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Detalles Bibliográficos
Autores principales: Ramond, Cyrille, Glaser, Nicolas, Berthault, Claire, Ameri, Jacqueline, Kirkegaard, Jeannette Schlichting, Hansson, Mattias, Honoré, Christian, Semb, Henrik, Scharfmann, Raphaël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540466/
https://www.ncbi.nlm.nih.gov/pubmed/28731406
http://dx.doi.org/10.7554/eLife.27564