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Dendritic cells that phagocytose apoptotic macrophages loaded with mycobacterial antigens activate CD8 T cells via cross-presentation

While homeostatic apoptosis is immunologically silent, macrophage apoptosis during Mycobacterium tuberculosis infection can potentially induce an immune response against the mycobacteria. To examine the role of dendritic cells in this response, macrophage apoptosis was induced by incubating the macr...

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Detalles Bibliográficos
Autores principales: Espinosa-Cueto, Patricia, Magallanes-Puebla, Alejandro, Castellanos, Carlos, Mancilla, Raul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540487/
https://www.ncbi.nlm.nih.gov/pubmed/28767693
http://dx.doi.org/10.1371/journal.pone.0182126