DNA mutation motifs in the genes associated with inherited diseases

Mutations in human genes can be responsible for inherited genetic disorders and cancer. Mutations can arise due to environmental factors or spontaneously. It has been shown that certain DNA sequences are more prone to mutate. These sites are termed hotspots and exhibit a higher mutation frequency th...

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Detalles Bibliográficos
Autores principales: Růžička, Michal, Kulhánek, Petr, Radová, Lenka, Čechová, Andrea, Špačková, Naďa, Fajkusová, Lenka, Réblová, Kamila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540541/
https://www.ncbi.nlm.nih.gov/pubmed/28767725
http://dx.doi.org/10.1371/journal.pone.0182377

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540541/
https://www.ncbi.nlm.nih.gov/pubmed/28767725
http://dx.doi.org/10.1371/journal.pone.0182377

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