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Insulin receptor signaling and glucagon-like peptide 1 effects on pancreatic beta cells

Glucagon-like peptide-1 (GLP-1) is a potent gluco-incretin hormone, which plays a central role on pancreatic beta cell proliferation, survival and insulin secreting activity and whose analogs are used for treating hyperglycemia in type 2 diabetes mellitus. Notably, abnormal insulin signaling affects...

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Detalles Bibliográficos
Autores principales: Caporarello, Nunzia, Parrino, Cristina, Trischitta, Vincenzo, Frittitta, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540605/
https://www.ncbi.nlm.nih.gov/pubmed/28767692
http://dx.doi.org/10.1371/journal.pone.0181190