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Drosophila LKB1 is required for the assembly of the polarized actin structure that allows spermatid individualization

In mammals, a testis-specific isoform of the protein kinase LKB1 is required for spermiogenesis, but its exact function and specificity are not known. Human LKB1 rescues the functions of Drosophila Lkb1 essential for viability, but these males are sterile, revealing a new function for this genes in...

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Detalles Bibliográficos
Autores principales: Couderc, Jean-Louis, Richard, Graziella, Vachias, Caroline, Mirouse, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540607/
https://www.ncbi.nlm.nih.gov/pubmed/28767695
http://dx.doi.org/10.1371/journal.pone.0182279