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LMP1-mediated glycolysis induces myeloid-derived suppressor cell expansion in nasopharyngeal carcinoma

Myeloid-derived suppressor cells (MDSCs) are expanded in tumor microenvironments, including that of Epstein–Barr virus (EBV)-associated nasopharyngeal carcinoma (NPC). The link between MDSC expansion and EBV infection in NPC is unclear. Here, we show that EBV latent membrane protein 1 (LMP1) promote...

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Detalles Bibliográficos
Autores principales: Cai, Ting-Ting, Ye, Shu-Biao, Liu, Yi-Na, He, Jia, Chen, Qiu-Yan, Mai, Hai-Qiang, Zhang, Chuan-Xia, Cui, Jun, Zhang, Xiao-Shi, Busson, Pierre, Zeng, Yi-Xin, Li, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540616/
https://www.ncbi.nlm.nih.gov/pubmed/28732079
http://dx.doi.org/10.1371/journal.ppat.1006503