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The Microbiome Activates CD4 T-cell–mediated Immunity to Compensate for Increased Intestinal Permeability

BACKGROUND & AIMS: Despite a prominent association, chronic intestinal barrier loss is insufficient to induce disease in human subjects or experimental animals. We hypothesized that compensatory mucosal immune activation might protect individuals with increased intestinal permeability from disea...

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Detalles Bibliográficos
Autores principales: Edelblum, Karen L., Sharon, Gil, Singh, Gurminder, Odenwald, Matthew A., Sailer, Anne, Cao, Severine, Ravens, Sarina, Thomsen, Irene, El Bissati, Kamal, McLeod, Rima, Dong, Chen, Gurbuxani, Sandeep, Prinz, Immo, Mazmanian, Sarkis K., Turner, Jerrold R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540699/
https://www.ncbi.nlm.nih.gov/pubmed/28795125
http://dx.doi.org/10.1016/j.jcmgh.2017.06.001