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The Microbiome Activates CD4 T-cell–mediated Immunity to Compensate for Increased Intestinal Permeability
BACKGROUND & AIMS: Despite a prominent association, chronic intestinal barrier loss is insufficient to induce disease in human subjects or experimental animals. We hypothesized that compensatory mucosal immune activation might protect individuals with increased intestinal permeability from disea...
Autores principales: | Edelblum, Karen L., Sharon, Gil, Singh, Gurminder, Odenwald, Matthew A., Sailer, Anne, Cao, Severine, Ravens, Sarina, Thomsen, Irene, El Bissati, Kamal, McLeod, Rima, Dong, Chen, Gurbuxani, Sandeep, Prinz, Immo, Mazmanian, Sarkis K., Turner, Jerrold R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540699/ https://www.ncbi.nlm.nih.gov/pubmed/28795125 http://dx.doi.org/10.1016/j.jcmgh.2017.06.001 |
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