Mass Cytometry Analysis Reveals Hyperactive NF Kappa B Signaling in Myelofibrosis and Secondary Acute Myeloid Leukemia

Myeloproliferative neoplasms (MPNs) feature a malignant clone containing the JAK2 V617F mutation, or another mutation causing dysregulated JAK2 kinase activity. The multiple disease phenotypes of MPNs, and their tendency to transform phenotypically, suggest pathophysiologic heterogeneities beyond a...

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Detalles Bibliográficos
Autores principales: Fisher, Daniel A.C., Malkova, Olga, Engle, Elizabeth K., Miner, Cathrine, Fulbright, Mary C., Behbehani, Gregory K., Collins, Taylor B., Bandyopadhyay, Shovik, Zhou, Amy, Nolan, Garry P., Oh, Stephen T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540814/
https://www.ncbi.nlm.nih.gov/pubmed/28008177
http://dx.doi.org/10.1038/leu.2016.377

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540814/
https://www.ncbi.nlm.nih.gov/pubmed/28008177
http://dx.doi.org/10.1038/leu.2016.377

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