Femtogram Level Sensitivity achieved by Surface Engineered Silica Nanoparticles in the Early Detection of HIV Infection

We have engineered streptavidin labelled Europium doped fluorescent silica nanoparticles which significantly increased sensitivity without compromising the specificity of the immunoassay. As a proof of concept, a time resolved fluorescence based sandwich immunoassay was developed to detect HIV-1 p24...

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Detalles Bibliográficos
Autores principales: Chunduri, L. A. Avinash, Kurdekar, Aditya, Haleyurgirisetty, Mohan Kumar, Bulagonda, Eswarappa Pradeep, Kamisetti, Venkataramaniah, Hewlett, Indira K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540927/
https://www.ncbi.nlm.nih.gov/pubmed/28769052
http://dx.doi.org/10.1038/s41598-017-07299-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540927/
https://www.ncbi.nlm.nih.gov/pubmed/28769052
http://dx.doi.org/10.1038/s41598-017-07299-1

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