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Femtogram Level Sensitivity achieved by Surface Engineered Silica Nanoparticles in the Early Detection of HIV Infection
We have engineered streptavidin labelled Europium doped fluorescent silica nanoparticles which significantly increased sensitivity without compromising the specificity of the immunoassay. As a proof of concept, a time resolved fluorescence based sandwich immunoassay was developed to detect HIV-1 p24...
Autores principales: | Chunduri, L. A. Avinash, Kurdekar, Aditya, Haleyurgirisetty, Mohan Kumar, Bulagonda, Eswarappa Pradeep, Kamisetti, Venkataramaniah, Hewlett, Indira K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540927/ https://www.ncbi.nlm.nih.gov/pubmed/28769052 http://dx.doi.org/10.1038/s41598-017-07299-1 |
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