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A System Dynamics Model to Predict the Human Monocyte Response to Endotoxins

System dynamics is a powerful tool that allows modeling of complex and highly networked systems such as those found in the human immune system. We have developed a model that reproduces how the exposure of human monocytes to lipopolysaccharides (LPSs) induces an inflammatory state characterized by h...

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Detalles Bibliográficos
Autores principales: Álvarez, Enrique, Toledano, Víctor, Morilla, Fernando, Hernández-Jiménez, Enrique, Cubillos-Zapata, Carolina, Varela-Serrano, Aníbal, Casas-Martín, José, Avendaño-Ortiz, José, Aguirre, Luis A., Arnalich, Francisco, Maroun-Eid, Charbel, Martín-Quirós, Alejandro, Quintana Díaz, Manuel, López-Collazo, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540970/
https://www.ncbi.nlm.nih.gov/pubmed/28824640
http://dx.doi.org/10.3389/fimmu.2017.00915