Few basepairing-independent motifs in the apical half of the avian HBV ε RNA stem-loop determine site-specific initiation of protein-priming

Hepadnaviruses, including human hepatitis B virus (HBV), replicate their tiny DNA genomes by protein-primed reverse transcription of a pregenomic (pg) RNA. Replication initiation as well as pgRNA encapsidation depend on the interaction of the viral polymerase, P protein, with the ε RNA element, feat...

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Detalles Bibliográficos
Autores principales: Gajer, Markus, Dörnbrack, Katharina, Rösler, Christine, Schmid, Bernadette, Beck, Jürgen, Nassal, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541001/
https://www.ncbi.nlm.nih.gov/pubmed/28769080
http://dx.doi.org/10.1038/s41598-017-07657-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541001/
https://www.ncbi.nlm.nih.gov/pubmed/28769080
http://dx.doi.org/10.1038/s41598-017-07657-z

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