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An alternative microRNA-mediated post-transcriptional regulation of GADD45A by p53 in human non-small-cell lung cancer cells

GADD45A (growth arrest and DNA damage inducible alpha), a stress response gene induced by genotoxic and nongenotoxic stresses, is implicated in various key processes, including the control of cell cycle checkpoints and DNA repair. The expression of GADD45A is directly regulated by numerous transcrip...

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Detalles Bibliográficos
Autores principales: Li, Jie, Dong, Jie, Li, Shaohua, Xia, Wei, Su, Xueting, Qin, Xingliang, Chen, Ying, Ding, Hongmei, Li, Hui, Huang, Aixue, Bai, Chenjun, Hu, Tongnan, Wang, Chenglong, Chu, Bingfeng, Shao, Ningsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541050/
https://www.ncbi.nlm.nih.gov/pubmed/28769054
http://dx.doi.org/10.1038/s41598-017-07332-3