Discovery of novel therapeutic properties of drugs from transcriptional responses based on multi-label classification

Drug repositioning strategies have improved substantially in recent years. At present, two advances are poised to facilitate new strategies. First, the LINCS project can provide rich transcriptome data that reflect the responses of cells upon exposure to various drugs. Second, machine learning algor...

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Detalles Bibliográficos
Autores principales: Xie, Lingwei, He, Song, Wen, Yuqi, Bo, Xiaochen, Zhang, Zhongnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541064/
https://www.ncbi.nlm.nih.gov/pubmed/28769090
http://dx.doi.org/10.1038/s41598-017-07705-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541064/
https://www.ncbi.nlm.nih.gov/pubmed/28769090
http://dx.doi.org/10.1038/s41598-017-07705-8

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