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Discovery of novel therapeutic properties of drugs from transcriptional responses based on multi-label classification
Drug repositioning strategies have improved substantially in recent years. At present, two advances are poised to facilitate new strategies. First, the LINCS project can provide rich transcriptome data that reflect the responses of cells upon exposure to various drugs. Second, machine learning algor...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541064/ https://www.ncbi.nlm.nih.gov/pubmed/28769090 http://dx.doi.org/10.1038/s41598-017-07705-8 |