The Role of Replication-Associated Repair Factors on R-Loops

The nascent RNA can reinvade the DNA double helix to form a structure termed the R-loop, where a single-stranded DNA (ssDNA) is accompanied by a DNA-RNA hybrid. Unresolved R-loops can impede transcription and replication processes and lead to genomic instability by a mechanism still not fully unders...

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Detalles Bibliográficos
Autores principales: Bhatia, Vaibhav, Herrera-Moyano, Emilia, Aguilera, Andrés, Gómez-González, Belén
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541304/
https://www.ncbi.nlm.nih.gov/pubmed/28653981
http://dx.doi.org/10.3390/genes8070171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541304/
https://www.ncbi.nlm.nih.gov/pubmed/28653981
http://dx.doi.org/10.3390/genes8070171

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