Cargando…

Aspergillus niger Prolyl Endoprotease for Hydrogen–Deuterium Exchange Mass Spectrometry and Protein Structural Studies

[Image: see text] To monitor the structural integrity of therapeutic proteins, hydrogen–deuterium exchange mass spectrometry (HDX-MS) is increasingly utilized in the pharmaceutical industry. The successful outcome of HDX-MS analyses depends on the sample preparation conditions, which involve the rap...

Descripción completa

Detalles Bibliográficos
Autores principales: Tsiatsiani, Liana, Akeroyd, Michiel, Olsthoorn, Maurien, Heck, Albert J. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541327/
https://www.ncbi.nlm.nih.gov/pubmed/28657298
http://dx.doi.org/10.1021/acs.analchem.7b01161