Cargando…

Theory of synergistic effects: Hill-type response surfaces as ‘null-interaction’ models for mixtures

BACKGROUND: The classification of effects caused by mixtures of agents as synergistic, antagonistic or additive depends critically on the reference model of ‘null interaction’. Two main approaches are currently in use, the Additive Dose (ADM) or concentration addition (CA) and the Multiplicative Sur...

Descripción completa

Detalles Bibliográficos
Autor principal: Schindler, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541435/
https://www.ncbi.nlm.nih.gov/pubmed/28768512
http://dx.doi.org/10.1186/s12976-017-0060-y