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Theory of synergistic effects: Hill-type response surfaces as ‘null-interaction’ models for mixtures
BACKGROUND: The classification of effects caused by mixtures of agents as synergistic, antagonistic or additive depends critically on the reference model of ‘null interaction’. Two main approaches are currently in use, the Additive Dose (ADM) or concentration addition (CA) and the Multiplicative Sur...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541435/ https://www.ncbi.nlm.nih.gov/pubmed/28768512 http://dx.doi.org/10.1186/s12976-017-0060-y |