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JWA regulates TRAIL-induced apoptosis via MARCH8-mediated DR4 ubiquitination in cisplatin-resistant gastric cancer cells

Platinum chemotherapeutics are widely used to treat solid malignant tumors, including gastric cancer (GC). Drug resistance to platinum compounds may result in cancer relapse and decreased survival. The identification and development of novel agents to reactivate apoptosis pathways in platinum-resist...

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Detalles Bibliográficos
Autores principales: Wang, Q, Chen, Q, Zhu, L, Chen, M, Xu, W, Panday, S, Wang, Z, Li, A, Røe, O D, Chen, R, Wang, S, Zhang, R, Zhou, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541709/
https://www.ncbi.nlm.nih.gov/pubmed/28671676
http://dx.doi.org/10.1038/oncsis.2017.57