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MeCP2, a target of miR-638, facilitates gastric cancer cell proliferation through activation of the MEK1/2–ERK1/2 signaling pathway by upregulating GIT1

Methyl-CpG binding protein 2 (MeCP2) is involved in the carcinogenesis and progression of multiple types of cancer. However, its precise role in gastric cancer (GC) and the relevant molecular mechanism remain unknown. In the present study, we found that miR-638 levels were lower in GC tissues and GC...

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Detalles Bibliográficos
Autores principales: Zhao, L Y, Tong, D D, Xue, M, Ma, H L, Liu, S Y, Yang, J, Liu, Y X, Guo, B, Ni, L, Liu, L Y, Qin, Y N, Wang, L M, Zhao, X G, Huang, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541712/
https://www.ncbi.nlm.nih.gov/pubmed/28759023
http://dx.doi.org/10.1038/oncsis.2017.60