Aspartate β-hydroxylase disrupts mitochondrial DNA stability and function in hepatocellular carcinoma

The mechanism of aberrant mitochondrial genome and function in hepatocellular carcinoma (HCC) remains largely unknown. Our previous study demonstrated an increased expression of aspartate β-hydroxylase (ASPH) in HCC tissues, which was associated with tumor invasiveness and a worse prognosis. Current...

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Detalles Bibliográficos
Autores principales: Tang, C, Hou, Y, Wang, H, Wang, K, Xiang, H, Wan, X, Xia, Y, Li, J, Wei, W, Xu, S, Lei, Z, Pawlik, T M, Wu, M, Shen, F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541716/
https://www.ncbi.nlm.nih.gov/pubmed/28714949
http://dx.doi.org/10.1038/oncsis.2017.64

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5541716/
https://www.ncbi.nlm.nih.gov/pubmed/28714949
http://dx.doi.org/10.1038/oncsis.2017.64

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